Concurrent Sessions

Sunday, May 7, 2006, 15.00 - 16.30 hrs - Auditorium

C01 Genetic analysis of complex disease I

C04. A genome-wide SNP association study of rheumatoid arthritis (RA) validates the DNA pooling approach
J. S. Lanchbury¹, A. Gutin¹, V. Abkevich¹, T. Merriman², S. Steer³, K. Timms¹, T. Tran¹, D. Shattuck¹, M. Skolnick¹;
¹Myriad Genetics, Inc., Salt Lake City, UT, United States, ²University of Otago, Auckland, New Zealand, ³GKT School of Medicine, King's College, London, United Kingdom.

C05. Copy Number Variation of NCF1 Gene is associated with Rheumatoid Arthritis but not with Psoriatic Arthritis
U. D. Hüffmeier¹, H. Burkhardt², C. T. Thiel¹, J. Lascorz¹, M. Streiter¹, B. Böhm², R. Holmdahl³, H. Schulze-Koops², A. Reis¹;
¹Human Genetics, University of Erlangen, Erlangen, Germany, ²Institute for Clinical Immunology and Rheumatology, Department of Internal Medicine III, University of Erlangen, Erlangen, Germany, ³Section for Medical Inflammation Research, Lund University, Lund, Sweden.

C06. Breaking loops for linkage analysis in complex pedigrees
T. I. Axenovich;
Institute of Cytology and Genetics, Novosibirsk, Russian Federation.

C07- Genome-wide screen for late onset Alzheimer’s disease in a complex pedigree from a genetically isolated population
F. Liu¹, A. Arias-Vásquez¹, Y. S. Aulchenko¹, K. Sleegers¹, P. Sanchez-Juan¹, A. M. Bertoli-Avella², B. J. Feng¹, A. Isaacs¹, P. Heutink³, C. van Broeckhoven⁴, B. A. Oostra², C. M. van Duijn¹;
¹Department of Epidemiology & Biostatistics, Erasmus MC, Rotterdam, The Netherlands, ²Department of Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands, ³Section Medical Genomics, Department of Human Genetics and Department of Biological Psychology, Center for Neurogenomics and Cognitive Research VU University and VU University Medical Center, Amsterdam, The Netherlands, ⁴Department of Molecular Genetics, Flanders Interuniversity, Institute of Biotechnology, University of Antwerp, B-2610 Antwerpen, Belgium.

C08. Genetic background of neurocognitive traits in schizophrenia and bipolar disorder - an association study in twins
O. P. H. Pietiläinen¹, T. Paunio¹, A. Loukola¹, A. Tuulio-Henriksson², T. Kieseppä², W. Hennah¹, J. A. Turunen¹, J. O. Peltonen¹, K. Silander¹, J. Lönnqvist², J. Kaprio^2,3, T. D. Cannon⁴, L. Peltonen^1,5;
¹National Public Health Institute, Department of Molecular Medicine, Biomedicum, P.O.Box 104, FIN-00251 Helsinki, Finland; e-mail: tiina.paunio@ktl.fi, Helsinki, Finland, ²National Public Health Institute, Department of Mental Health and Alcohol Research, Helsinki, Finland, ³University of Helsinki, Department of Public Health, Helsinki, Finland, ⁴UCLA, Departments of Psychology and Psychiatry and Biobehavioral Sciences, Los Angeles, CA, United States, ⁵University of Helsinki, Department of Medical Genetics, Helsinki, Finland.

C09. Differential liabilities of coding and non-coding mutations at a major locus in complex disease : RET in Hirschsprung disease
J. Amiel¹, G. Antinolo², S. Borrego², G. Burzynski³, I. Ceccherini⁴, E. Emison⁵, C. Eng⁶, R. Fernandez², M. Garcia-Barcelo⁷, P. Griseri⁴, R. Hofstra³, C. Kashuk⁵, F. Lantieri⁴, S. Lyonnet¹, P. Tam⁷, A. Tullio-Pelet¹, K. West⁵, A. Chakravarti⁵;
¹Necker, Paris, France, ²UC Genetica y Reproduccion, HH UU Virgen del Rocio, Seville, Spain, ³Dept Medical Genetics, Groningen, The Netherlands, ⁴Lab di Genetica Molecolare, Ist Gaslini, Genova, Italy, ⁵Inst Genetic Medicine, Johns Hopkins Univ, Baltimore, MD, United States, ⁶Dept Molecular Genetics, Ohio State Univ, Columbus, OH, United States, ⁷Dept Surgery, Genome Research Centre, Univ Hong Kong, Hong Kong, China.