CANCELLED ES1. Clinical genetics, skeletal dysplasia (Geert Mortier)
ES2. Movement disorders, Clinical and molecular diagnosis (Olaf Rieß)
ES3. Complex genetics: Asthma as an example (Juha Kere)
ES4. Molecular cytogenetics in practice (Nigel Carter)

Welcoming Addresses
ESHG Education Awards
The Education Award 2007 of the European Society of Human Genetics will be presented to Professors Tom Strachan and Andrew Read for their outstanding contribution to the dispersal of knowledge of modern human molecular genetics among students and professionals.

• Establishment and hereditary transmission of epigenetic modifications and pathological developments: the mouse model
  François Cuzin, Nice, France
   
• DNA Repair, genome maintenance and human disease
  Miroslav Radman, Paris, France
   
• Human neuroimaging - contributions to neurogenetics
  Richard Frackowiak, London, United Kingdom

PL04
Neurodegeneration in lysosomal storage diseases is associated with impairment of autophagy
A. Fraldi¹, C. Settembre¹, C. Spampanato¹, R. de Pablo¹, D. L. Medina¹, L. Jahreiss², A. Lombardi¹, C. Venturi³, C. Tacchetti³, D. C. Rubinsztein², A. Ballabio^1,4;
¹Telethon Institute of Genetics and Medicine (TIGEM), Naples, Italy, ²Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom, ³Department of Experimental Medicine and §MicroSCoBiO Research Center and IFOM Center of Cell Oncology and Ultrastructure, University of Genoa, Genoa, Italy, ⁴Medical Genetics, Department of Pediatrics, Federico II University, Naples, Italy.

PL05
Identification of 3 novel genes that cause X-linked mental retardation; AP1S2, CUL4B and ZDHHC9.
F. Raymond¹, P. Tarpey², G. Turner³, R. Stevenson⁴, C. Schwartz⁴, J. Gecz⁵, P. Futreal², M. Stratton², on behalf of the GOLD (Genetics of Learning Disability) study;
¹Cambridge Institute for Medical Research, Cambridge, United Kingdom, ²Sanger Institute, Cambridge, United Kingdom, ³University of Newcastle, Newcastle, Australia, ⁴JC Self Research Institute of Human Genetics, Greenwood, SC, United States, ⁵University of Adelaide, Adelaide, Australia.

PL06
Mutations in LRP2, coding for the multi-ligand receptor megalin, cause Donnai-Barrow and Faciooculoacousticorenal (FOAR) syndromes
S. Kantarci¹, L. Al-Gazali², R. Hill³, D. Donnai⁴, G. C. M. Black⁴, E. Bieth⁵, N. Chassaing^5,6, D. Lacombe⁶, K. Devriendt⁷, A. Teebi⁸, M. Loscertales¹, C. Robson⁹, T. Liu¹⁰, D. T. MacLaughlin¹, K. M. Noonan¹, M. K. Russell¹, C. A. Walsh^3,9, P. K. Donahoe¹, B. R. Pober^1,9;
¹Massachusetts General Hospital, Boston, MA, United States, ²UAE University, Al Ain, United Arab Emirates, ³Beth Israel Deaconess Medical Center, Boston, MA, United States, ⁴University of Manchester and St Mary’s Hospital, Manchester, United Kingdom, ⁵Hopital Purpan, Toulouse, France, ⁶Hôpital Pelligrin, Bordeaux, France, ⁷University of Leuven, Leuven, Belgium, ⁸Weill Cornell Medical College in Qatar and Hamad Medical City, Doha, Qatar, ⁹Children's Hospital, Boston, MA, United States, ¹⁰Brigham and Women's Hospital, Boston, MA, United States.

PL07
RAB23 mutations in Carpenter syndrome imply an unexpected role for Hedgehog signaling in cranial suture development and obesity
D. Jenkins¹, D. Seelow², F. S. Jeehee³, C. A. Perlyn⁴, L. G. Alonso⁵, D. F. Bueno⁶, D. Donnai⁷, D. Josifiova⁸, I. M. J. Mathijssen⁹, J. E. V. Morton¹⁰, K. Orstavik¹¹, E. Sweeney¹², S. A. Wall¹³, J. L. Marsh¹⁴, P. Nurnberg², M. Passos-Bueno¹⁵, A. O. M. Wilkie¹;
¹Weatherall Institute of Molecular Medicine, Oxford, United Kingdom, ²Cologne Center for Genomics and Institute for Genetics, Cologne, Germany, ³Centro de Estudos de Genomca Humano, Sao Paulo, Brazil, ⁴Washington University School of Medicine, St Louis, MO, United States, ⁵Universidade Federal de Sao Paulo, Sao Paulo, Brazil, ⁶Universidade de Campinas, Sao Paulo, Brazil, ⁷University of Manchester, Manchester, United Kingdom, ⁸Guy's Hospital, London, United Kingdom, ⁹Erasmus Medical Center, Rotterdam, The Netherlands, ¹⁰Birmingham Women's Hospital, Birmingham, United Kingdom, ¹¹Rikshospitalet-Radiumhospitalet Medical Centre, Oslo, Norway, ¹²Liverpool Women's Hospital, Liverpool, United Kingdom, ¹³John Radcliffe Hospital, Oxford, United Kingdom, ¹⁴St John's Mercy Medical Center, St Louis, MO, United States, ¹⁵Universidade de Sao Paulo, Sao Paulo, Brazil.

PL08
Y chromosome detection by Real Time PCR and pyrophosphorolysis-activated polymerization using free fetal DNA isolated from maternal plasma.
H. B. Schlecht¹, E. M. J. Boon², P. Martin³, G. Daniels³, R. H. A. M. Vossen⁴, J. T. den Dunnen⁴, B. Bakker², R. Elles¹;
¹National Genetics Reference Laboratory, Manchester, United Kingdom, ²Leiden University Medical Centre, Leiden, The Netherlands, ³International Blood Group Reference Centre, Bristol, United Kingdom, ⁴Leiden Genome Technology Centre, Leiden, The Netherlands.

• The increasing impact of internet on genetic services.
  Segolene Aymé, Paris, France
   
• Is there a role for the Human Geneticist in the genomic revolution
  Charles Epstein, San Francisco, CA
   
• What do we do with 1000 € genome?
  Marcus Pembrey, Bristol, United Kingdom

S02. miRNAs and the RNA world
Chair: A. Read, T. Frébourg

• What miRNAs do
  Scott Hammond, Chapell Hill, United States
   
• Small RNAs in gametogenesis
  Angélique Girard, Cold Spring Harbor, United States
   
• Vertebrate miRNA diversity
  Edwin Cuppen, Utrecht, NL

• SLE susceptibility genes
  Tim J. Vyse, London, United Kingdom
   
• New pathways in pathogenesis of allergic asthma: ADAM33 and end organ susceptibility genes
  John Holloway, Southampton, United Kingdom
   
• Genetic and environmental factors in celiac disease
  Ludvig Sollid, Oslo, Norway

• The genetic architecture of Skin pigmentation
  Mark Shriver, University Park, PA, United States
   
• Novel Insights into melanoma genetics
  Boris C. Bastian, San Francisco, CA, United States
   
• Coat colour mutants and melanocyte signalling pathways
  Bill Pavan, Bethesda, MD, United States

W1. Syndrome identification I, D. Donnai, J. Clayton-Smith
W2. Community genetics, M. Cornel, U. Kristoffersson, L. ten Kate
W3. Quality control, E. Dequeker, M. Morris
W4. Cytogenetics, M. Vekemans, J.C.K. Barber
W5. Preimplantation genetic diagnosis, M. Macek Jr., A. Corveleyn
W6. 22q11 disorders (Molecular genetics and clinical aspects), B. Emmanuel, B. Morrow

• C01 Clinical Genetics I
  Apollon
   
• C02 Molecular and biochemical basis of disease I
  Athéna
   
• C03 Complex disease and population genetics
  Thalie + Erato
   
• C04 New technological advances in genomics
  Hermès
   
• C05 Prenatal diagnosis
  Méditerranée
  

• Laterality and laterality disorders
  Judith Goodship, Newcastle upon Tyne, United Kingdom
   
• Molecular basis of primary ciliary dyskinesia
  Serge Amselem, Créteil, France
   
• Bardet Biedl disease
  Philip Beales, London, United Kingdom

• Towards a gene expression map of human brain development
  Susan Lindsay, Newcastle upon Tyne, United Kingdom
   
• Genetic and genomic studies of patterning in the human cerebral cortex
  Christopher A. Walsh, Boston, MA, United States
   
• Signalling Pathways deduced from the analysis of spatial gene expression patterns
  G. Eichele, Göttingen, Germany

• Thalassemia and SNPs
  Douglas R. Higgs, Oxford, United Kingdom
   
• Chromosome dynamics in gene regulation
  Charalambos G. Spilianakis, New Haven, CT, United States
   
• Molecular mechanisms of congenital hyperinsulinism
  Pascale de Lonlay, Paris, France

S08. Cancer stem cells and cell lineage commitment
Chair: D. Aberdam, P. Lichter

• Bone marrow derived stem cells and cancer: from the perspective of gastric cancer
  Jean-Marie Houghton, Worcester, MA, United States
   
• Stem cell renewal and the Nanog gene
  Austin Smith, Cambridge, United Kingdom
   
• The role of Pax5 in B-cell commitment and lymphomagenesis
  Meinard Busslinger, Vienna, Austria

• Neurodegenerative dementias
  Christine Van Broeckhoven, Antwerp, Belgium
   
• Daring clinical trials in Friedreich ataxia? Iron and irony of fate
  Arnold Munnich, Paris, France
   
• Huntington pathogenesis
  Frédéric Saudou, Paris, France

W7. Syndrome identification II, D. Donnai, J. Clayton-Smith
W8. Genetics education, D. Coviello, L. ten Kate
W9. Non invasive prenatal diagnosis, M. Hulten, L. Chitty
W10. History of (cyto)genetics, C. Yapiyakis
W11. Users discussion on array platforms, P. Lichter, N. Carter
W12. Mutation nomenclature and disease-gene mutation databases, J. den Dunnen

• C06 Clinical Genetics II
  Apollon
   
• C07 Molecular and biochemical basis of disease II
  Athéna
   
• C08 Analysis of complex diseases
  Thalie + Erato
   
• C09 Cancer genetics
  Hermès
   
• C10 Therapy for genetic disease
  Méditerranée

• NFAT pathway
  Isabella Graef, Stanford, CA, United States
   
• The Tc1 mouse, an aneuploid mouse with a human chromosome that models aspects of Down syndrome
  Elizabeth Fisher, London, United Kingdom
   
• Copy number variation in the human genome
  Stephen W. Scherer, Toronto, Canada

• Polymorphic miRNA-mediated gene regulation: contribution to phenotypic variation and disease
  Michel Georges, Liege, Belgium
   
• Epigenetics and X-inactivation
  Claire Rougeulle, Paris, France
   
• Methylation and colorectal cancer
  Miguel A. Peinado, Barcelona, Spain

• Testing and estimation of genotype and haplotype effects in case/control and family-based association studies
  Heather Cordell, Newcastle upon Tyne, United Kingdom
   
• Genotyping on large-scale platforms
  Markus Nöthen, Bonn, Germany
   
• Large population studies
  Bill Ollier, Manchester, United Kingdom

• Cell division and modelling cancer in Drosophila
  Cayetano Gonzalez, Barcelona, Spain
   
• How is time controlled during embryonic development? Lessons from the chick embryo
  Fernanda Bajanca, Braga, Portugal
   
• Conditional gene targeting to model human diseases in mice
  Klaus Rajewsky, Boston, MA, United States

• What is a modifier gene?
  Aravinda Chakravarti, Baltimore, MD, United States
   
• Is the candidate gene approach a good way to find CF modifiers?
  Mitchell L. Drumm, Cleveland, OH, United States
   
• Genes that modify iron loading in mice
  Nancy Andrews, Boston, MA, United States 
   
• Genetic Modulation of Sickle Cell Anemia
  Martin H. Steinberg, Boston, MA, United States

• Biochemistry and genetics of mitochondrial fatty-acid oxidation disorders
  Ronald J.A. Wanders, Amsterdam, The Netherlands
   
• Glycosylation defects
  Gert Matthijs, Leuven, Belgium
   
• Pyridoxine metabolism
  Peter Clayton, London, United Kingdom

• APC Genes
  Inke Näthke, Dundee, United Kingdom
   
• Wt1 acts at multiple stages during kidney development
  Andreas Schedl, Nice, France
   
• Making eyes: lessons from ocular malformations
  Veronica van Heyningen, Edinburgh

• C11 Molecular and biochemical basis of disease III
  Apollon
   
• C12 Genomics
  Athéna
   
• C13 Cytogenetics
  Thalie + Erato
   
• C14 Genetic counselling and public understanding of genetics
  Hermès

Intracellular Protein Degradation: From a Vague Idea thru the Lysosome and the Ubiquitin-Proteasome System and onto Human Diseases and Drug Targeting
Aaron J. Ciechanover, Haifa, Israel
(Nobel prize in Chemistry 2004)

Pictures can be found here

Journal Awards
Young Investigator Awards
A list of Awardees of the 2007 Meeting as well as a picture gallery of the awarding ceremony can be found here.

ESHG Award Lecture by Andrea Ballabio: Adventures in Genetic Diseases: travelling from phenotypes to gene mutations on a return ticket

Pictures can be found here

Closing

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